Found 24 matching trials
A Safety and Efficacy Study of Oral Cladribine in Subjects With Relapsing-remitting Multiple Sclerosis (RRMS)
PHASE3The purpose of the study is to determine if cladribine tablets are a safe a...
Location
Multiple Locations
Oral Cladribine B-cell Study
N/ATo study the impact of cladribine on peripheral and intrathecal B-cell, pla...
Location
Barts Health NHS Trust
ChariotMS - Cladribine to Halt Deterioration in People With Advanced Multiple Sclerosis
PHASE2MS is a chronic inflammatory and degenerative disease of the central nervou...
Status
Active Not Recruiting
Location
Queens University Belfast (Belfast Health and Social Care Trust)
Norwegian Study of Oral Cladribine and Rituximab in Multiple Sclerosis (NOR-MS)
PHASE3The main aim and overall objective of the study is to assess whether rituxi...
Location
Department of Neurology - Drammen, Vestre Viken HF
Safety and Efficacy of Cladribine Therapy After Anti CD20 Therapy
N/AProlonged anti CD20 therapy for the treatment of active multiple sclerosis ...
Location
Neurocenter of Southern Switzerland, Ospedale Regionale di Lugano
A Phase 2 Study of Cladribine Add-on to Interferon-beta (IFN-beta) Therapy in Multiple Sclerosis (MS) Subjects With Active Disease (ONWARD)
PHASE2The goal of this study was to evaluate the safety, tolerability and effecti...
Cladribine Tablets: Collaborative Study to Evaluate Impact On Central Nervous System Biomarkers in Multiple Sclerosis
PHASE4The purpose of this study is to better understand the mechanism of action (...
Location
Washington University School of Medicine
A Prospective Biomarker Study in Active SPMS Subjects Treated With Cladribine Tablets
PHASE4The purpose of this study is to explore the concept that biomarker sensitiv...
Location
Multiple Sclerosis Center of Northeastern New York, P.C.
A Study of Suboptimally Controlled Participants Previously Taking Injectable DMDs for RMS (CLICK-MS)
N/ATo evaluate the effectiveness, patient-reported outcomes (PROs) and safety ...
Location
University of Arkansas for Medical Sciences
Traditional Versus Early Aggressive Therapy for Multiple Sclerosis Trial
NAFDA-approved multiple sclerosis (MS) disease-modifying therapies (DMTs) tar...
Status
Active Not Recruiting
Location
University of Alabama at Birmingham
Treatments Being Tested
Natalizumab/natalizumab-sztn, Alemtuzumab, Ocrelizumab, Rituximab/rituximab-arrx/rituximab-abbs/rituximab-pvvr, Cladribine, Ofatumumab, Ublituximab-xiiy, Ocrelizumab and hyaluronidase-ocsqGlatiramer acetate, Interferons (intramuscular, subcutaneous, pegylated) Teriflunomide, Fumarates (dimethyl, diroximel, monomethyl) Fingolimod, Siponimod, Ozanimod, Ponesimod